Empresa:

Valvian

Descrição da Função

About Valvian

Valvian is a biotechnology company focused on developing advanced therapies for oncology and age related diseases.

Role Mission

The Senior Researcher will drive experimental research on cellular senescence, immune modulation and aging-related pathways. This role is hands-on in the laboratory, contributing directly to the scientific foundation of Valvian's longevity pipeline and supporting early therapeutic programs.

Key Responsibilities

1. Experimental research

• Design and execute in vitro experiments related to senescence, inflammaging, immune function and metabolic stress.

• Perform assays such as flow cytometry, cytokine profiling, phenotypic screening, transcriptomics sample prep and senescence markers.

• Analyse and interpret experimental data and provide clear documentation.

2. Target and biomarker exploration

• Investigate pathways associated with aging and age-related immune dysfunction.

• Support the identification and validation of targets relevant to senescence clearance, immune rejuvenation and metabolic regulation.

3. Collaboration with AI and multi-omics

• Provide curated biological data to the AI team.

• Test experimentally the biological hypotheses and predictions generated by computational models.

• Contribute to integrated analyses combining omics datasets (transcriptomics, proteomics, glycomics).

4. Support for preclinical program development

• Assist in generating data packages for internal decision points and external partners.

• Conduct preliminary efficacy and mechanism-of-action studies.

• Prepare material for presentations, internal reviews and investors when needed.

5. Laboratory operations

• Ensure proper documentation, reproducibility and adherence to good laboratory practices.

• Help maintain equipment, reagents and lab workflows in coordination with the lab manager.

• Mentor junior researchers or interns when appropriate.

Candidate Profile

Education

• PhD in Cell Biology, Immunology, Biotechnology, Gerontology, Molecular Biology or related fields.

Experience

• 3 to 7 years of research experience in areas such as aging biology, senescence, chronic inflammation, immune cell biology or metabolic stress.

• Strong track record of hands-on lab work and experimental design.

• Experience with multi-omics or computational biology is a plus, but not required.

• Previous biotech experience is appreciated but not mandatory.

Skills

• Excellent wet-lab experimental skills.

• Ability to analyse complex datasets and derive biological insights.

• Strong scientific writing skills.

• Proactive, organised and execution-oriented.

• Comfortable working in a fast-paced biotech environment.

What We Offer

• Opportunity to join a high-growth biotech shaping the future of healthy aging.

• Exposure to cutting-edge science combining wet lab, glycobiology and AI.

• Direct contribution to early discovery and preclinical programs.

• Collaboration with international centres and senior scientists.

Observações

Lisboa (Portugal)